Drugs Online » Prescription Drugs 12 » Ovestin Generic Oestriol
Indications:Atrophy of the lower urogenital tract related to oestrogen deficiency notably1.For the treatment of vaginal complaints such as dyspareunia dryness and itching. for the prevention of recurrent infections of the vagina and lower urinary tract. 2.In the management of micturition complaints (such as frequency and dysuria) and mild urinary incontinence. Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery.3.Climacteric complaints such as hot flushes and night sweating.4.A diagnostic aid in case of a doubtful atrophic cervical smear.5.Infertility due to cervical hostility.Dosage And Administration:Dosage:Atrophy of the lower urogenital tract: 4-8mg per day for the first weeks followed by a gradual reduction based on relief of symptoms until a maintenance dosage (e.g. 1-2mg per day) is reached. Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery:4-8mg per day in the 2 weeks before surgery; 1-2mg per day in the 2 weeks after surgery.Climacteric complaints such as hot flushes and night sweating:4-8mg per day during the first weeks followed by a gradual reduction. The lowest effective dosage should be used. In case of long-term treatment in women with an intact uterus monitoring of the endometrium or alternatively concomitant use of a progestagen is recommended A diagnostic aid in case of a doubtful atrophic cervical smear2-4mg per day for 7 days before taking the next smear.Infertility due to cervical hostilityIn general 1-2mg per day on days 6-15 of the menstrual cycle. However for some patients dosages as low as 1mg per day are sufficient whereas others may need up to 8mg per day. Therefore the dosage should be increased each month until an optimal effect on the cervical mucus is obtained.AdministrationA missed dose should be taken as soon as remembered unless it is more than 12 hours overdue. In the latter case the missed dose should be skipped and the next dose should be taken at the normal time. The tablets should be swallowed with some water or other drink preferably at the same time every day. It is important that the total daily dose is taken at one time.For initiation and continuation of treatment of postmenopausal symptoms the lowest effective dose for the shortest duration of time should be used (see also Warnings and Precautions).In women not taking HRT or women who switch from a continuous combined HRT product treatment with OVESTIN may be started on any day. Women who switch from cyclic HRT regimen should start OVESTIN treatment one week after completion of the cycle.
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Ovestin ( Generic Oestriol )
Ovestin (Generic Oestriol)
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From Gulf News: Runners should avoid prescription drugs. Statins may increase production of the enzyme creatine kinase, and hence heighten chances of muscle damage in athletes. Marathon running has increased in popularity over the past three decades, with participation in the United States rising from 25,000 runners in 1976 to nearly 470,000 in 2008. Many professional and recreational runners take prescription drugs, unaware of potential side-effects that affect runners in particular. One such class of drugs, called statins, which includes medicines such as Lipitor, Crestor and Pravachol, lowers blood cholesterol by inhibiting a cholesterol-producing enzyme and may even lower the risks of heart attack and further cardiovascular disease in a narrow category of patients. A new study forthcoming in the American Journal of Cardiology examined the effect of statins on creatine kinase (CK), an enzyme linked to muscle damage. Elevated levels of CK in the blood and muscle after exercise correlates with muscle damage. The study, conducted by Dr Beth Parker of the Henry Low Heart Centre at Connecticut's Hartford Hospital, is the first to measure CK levels in athletes taking statins after physical activity in a real-life environment rather than in a university laboratory.


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