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Sildenafil is used to treat male sexual function problems (impotence or erectile dysfunction) by blocking a certain enzyme (phosphodiesterase-PDE5) in the body. In combination with sexual stimulation sildenafil works by helping the blood flow into the penis to achieve and maintain an erection.This drug is not indicated for use in women.Use of this drug does not protect against sexually transmitted diseases (e.g. HIV hepatitis B gonorrhea syphilis). Practice "safe sex" such as using latex condoms. Consult your doctor or pharmacist for more details.How to use Kamagra OralRead the Patient Information Leaflet provided by your pharmacist before you start taking sildenafil and each time you get a refill. If you have any questions consult your doctor or pharmacist.This drug is taken by mouth as needed at least 30 minutes but no more than 4 hours before sexual activity (1 hour before is the most effective). Do not take more often than once daily and take as directed.A high fat meal may delay the time of onset of this drug.Avoid eating grapefruit or drinking grapefruit juice while you are being treated with this medication unless your doctor instructs you otherwise.The dosage is based on your medical condition response to therapy and other medications you may be taking (see also Drug Interactions section). Consult your doctor or pharmacist for more details.
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From Gulf News: Runners should avoid prescription drugs. Statins may increase production of the enzyme creatine kinase, and hence heighten chances of muscle damage in athletes. Marathon running has increased in popularity over the past three decades, with participation in the United States rising from 25,000 runners in 1976 to nearly 470,000 in 2008. Many professional and recreational runners take prescription drugs, unaware of potential side-effects that affect runners in particular. One such class of drugs, called statins, which includes medicines such as Lipitor, Crestor and Pravachol, lowers blood cholesterol by inhibiting a cholesterol-producing enzyme and may even lower the risks of heart attack and further cardiovascular disease in a narrow category of patients. A new study forthcoming in the American Journal of Cardiology examined the effect of statins on creatine kinase (CK), an enzyme linked to muscle damage. Elevated levels of CK in the blood and muscle after exercise correlates with muscle damage. The study, conducted by Dr Beth Parker of the Henry Low Heart Centre at Connecticut's Hartford Hospital, is the first to measure CK levels in athletes taking statins after physical activity in a real-life environment rather than in a university laboratory.


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