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Damizol (Diloxanide Furoate / Metronidazole) |
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Drugs Online » Gastrointestinal » Damizol (Diloxanide Furoate / Metronidazole) Damizol is a combination of diloxanide furoate and metronidazole useful in the treatment of intestinal and extra intestinal amoebic infections. Diloxanide furoate is a luminal amoebicide acting on the amoebic cyst and trophozite within the lumen of the bowel. Metronidazole is a tissue amoebicide affecting the parasite in the intestinal wall or other organs. Buy Damizol (Diloxanide Furoate / Metronidazole) and other Gastrointestinal products online at Medstore. Buy Online at Medstore - Click Here!
About Damizol (Diloxanide Furoate / Metronidazole): Product Type: Gastrointestinal Brand name: Damizol Generic name: Diloxanide Furoate / Metronidazole Properties Damizol is a combination of diloxanide furoate and metronidazole useful in the treatment of intestinal and extraintestinal amoebic infections. Diloxanide furoate is a luminal amoebicide acting on the amoebic cyst and trophozite within the lumen of the bowel. Metronidazole is a tissue amoebicide affecting the parasite in the intestinal wall or other organs. Through its binding to the DNA present inside the cell and preventing it from multiplication. Indications Damizol is indicated in the treatment of acute and chronic intestinal amoebiasis including the amoebic cyst carriers hepatitis amoebic liver abscess and other systemic infections caused by E. histolytica and giardiasis. Contraindications: Hypersensitivity to the components of the formulation. Side Effects Occasional mild gastrointestinal disturbances: • Abdominal pain distention nausea burning sensation in the tongue headache and dizziness. Precautions: • Anticoagulants: Metronidazole increases blood levels of warfarin and other oral coumarin anticoagulants resulting in prolongation of prothrombin time. • Drugs affecting liver enzyme activity: The simultaneous administration of drugs that induce microsomal liver enzymes such as phenytoin or phenobarbital may accelerate the elimination of metronidazole resulting in reduced plasma levels. The simultaneous administration of drugs that decrease microsomal liver enzyme activity such as cimetidine may prolong the half-life and decrease plasma clearance of metronidazole. • Alcohol: Alcoholic beverages should not be consumed during metronidazole therapy and for at least one day afterwards because abdominal cramps nausea vomiting headaches and flushing may occur. • Pregnancy: The drug should be avoided during pregnancy particularly during the first trimester. • Nursing Mothers: Metronidazole is secreted in breast milk. The drug should be avoided by nursing mothers. • In the elderly: In elderly patients the pharmacokinetics of metronidazole may be altered and monitoring of serum levels may be necessary. • In imparid hepatic function: Patients with severe hepatic disease metabolize metronidazole slowly hence dosage adjustments in this category of patients may be required. • This preparation may reduce the effectiveness of the combined oral contraceptives. Other conditions: • Blood disorders. • Diseases of the central nervous system (brain and spinal cord). Dosage Damizol should be taken with food. When on Dailozole alcoholic beverages should be avoided. The patient should be advised to complete the course. Adults: Two tablets thrice daily for five days. Extended treatment for ten days in refractory cases. Children (5 — 12 years): Half tablet — one tablet thrice daily for five days. Generic Damizol (Diloxanide Furoate / Metronidazole) Damizol (Diloxanide Furoate / Metronidazole) 250/200mg 100 tabs 250/200mg 150 tabs 250/200mg 250 tabs 250/200mg 200 tabs 250/200mg 300 tabs Diloxanide Furoate / Metronidazole Damizol
View more Gastrointestinal Drugs Online: From Gulf News: Runners should avoid prescription drugs. Statins may increase production of the enzyme creatine kinase, and hence heighten chances of muscle damage in athletes. Marathon running has increased in popularity over the past three decades, with participation in the United States rising from 25,000 runners in 1976 to nearly 470,000 in 2008. Many professional and recreational runners take prescription drugs, unaware of potential side-effects that affect runners in particular. One such class of drugs, called statins, which includes medicines such as Lipitor, Crestor and Pravachol, lowers blood cholesterol by inhibiting a cholesterol-producing enzyme and may even lower the risks of heart attack and further cardiovascular disease in a narrow category of patients. A new study forthcoming in the American Journal of Cardiology examined the effect of statins on creatine kinase (CK), an enzyme linked to muscle damage. Elevated levels of CK in the blood and muscle after exercise correlates with muscle damage. The study, conducted by Dr Beth Parker of the Henry Low Heart Centre at Connecticut's Hartford Hospital, is the first to measure CK levels in athletes taking statins after physical activity in a real-life environment rather than in a university laboratory.
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