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Dacarbazine is an anticancer (cytotoxic) medicine.Cancers form when some cells within the body multiply uncontrollably and abnormally. There are two types of cancer. Solid cancers where a lump forms e.g. the bone muscle brain cells etc. divide and multiply abnormally. The second type are leukaemias and lymphomas where the blood cells divide and multiply abnormally.Other characteristics of cancer besides uncontrolled growth include the ability of these abnormal cells to invade other tissues next to them or to break away from the original site travel through the blood or lymph and establish a new cancer at a different site of the body. These are called metastases.Like normal healthy cells cancer cells go through a continuous process of change. Each cell divides into two daughter cells. These cells grow rest and then divide again. The medicines used in chemotherapy are powerful chemicals designed to interupt this cycle and stop cells from growing.Several different types of anticancer medicines are used in chemotherapy. Each type kills cells at a different stage of the cell's life cycle. Each does its job in a different way.Dacarbazine is a synthetic compound. It works by blocking the production of genetic material (DNA) in the cell by binding it together. This prevents the cell from growing and therefore it dies.Unfortunately anticancer medicines will also affect the growth and division of normal healthy cells in the same way such as blood gut and hair cells. This can therefore cause several of the side effects seen with chemotherapy e.g. hair loss. The body's immune system also becomes suppressed increasing the risk of infections.In most chemotherapy regimens doses are administered in courses at various intervals to allow normal cells to recover from the adverse effects of the anticancer medicines between doses. However during this period cancer cells will also recover and start to replicate again. Successful treatment depends on the administration of the next course of therapy before the cancer has regrown to its previous size and the net effect is to decrease the amount of cancer with each successive course.Dacarbazine is used in combination with other anticancer medicines. It is administered by intravenous infusion.What is it used for?Breast cancer Cancer of the colon (large bowel) Cancer of the ovaries Cancer of the soft tissue e.g. muscle (soft tissue sarcoma)Lung cancer Lymph node cancer (Hodgkin's disease) Metastatic cancerous melanoma Testicular cancer
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DACARB ( Generic Dacarbazine )
DACARB (Generic Dacarbazine)
Generic Dacarbazine
200MG 16 Tablets
Generic Dacarbazine DACARB

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From Gulf News: Runners should avoid prescription drugs. Statins may increase production of the enzyme creatine kinase, and hence heighten chances of muscle damage in athletes. Marathon running has increased in popularity over the past three decades, with participation in the United States rising from 25,000 runners in 1976 to nearly 470,000 in 2008. Many professional and recreational runners take prescription drugs, unaware of potential side-effects that affect runners in particular. One such class of drugs, called statins, which includes medicines such as Lipitor, Crestor and Pravachol, lowers blood cholesterol by inhibiting a cholesterol-producing enzyme and may even lower the risks of heart attack and further cardiovascular disease in a narrow category of patients. A new study forthcoming in the American Journal of Cardiology examined the effect of statins on creatine kinase (CK), an enzyme linked to muscle damage. Elevated levels of CK in the blood and muscle after exercise correlates with muscle damage. The study, conducted by Dr Beth Parker of the Henry Low Heart Centre at Connecticut's Hartford Hospital, is the first to measure CK levels in athletes taking statins after physical activity in a real-life environment rather than in a university laboratory.


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