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Entacapone is an inhibitor of catechol-O-methyltransferase (COMT). It is used in combination with levodopa and carbidopa (Sinemet) to treat the end-of-dose 'wearing-off' symptoms of Parkinson's disease. Entacapone helps the levodopa and carbidopa work better by allowing more of it to reach the brain where it has its effects.Entacapone comes as a tablet to take by mouth. It is taken with every dose of levodopa and carbidopa up to 8 times a day. Entacapone may be taken with or without food. Read your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Take entacapone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.Entacapone helps control the symptoms of Parkinson's disease but it does not cure it. Continue to take entacapone even if you feel well. Do not stop taking entacapone without talking to your doctor. Stopping entacapone suddenly may make your Parkinson's disease worse and could have other dangerous effects. Your doctor probably will decrease your dose gradually if necessary.
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Product Type: Prescription Drugs 1
Adacapone ( Comtan Generic Entacapone )
Adacapone (Comtan Generic Entacapone)
Comtan Generic Entacapone
200mg 200 (4 x 50) Tablets 50 Tablets 100 (2 x 50) Tablets
Comtan Generic Entacapone Adacapone

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From Gulf News: Runners should avoid prescription drugs. Statins may increase production of the enzyme creatine kinase, and hence heighten chances of muscle damage in athletes. Marathon running has increased in popularity over the past three decades, with participation in the United States rising from 25,000 runners in 1976 to nearly 470,000 in 2008. Many professional and recreational runners take prescription drugs, unaware of potential side-effects that affect runners in particular. One such class of drugs, called statins, which includes medicines such as Lipitor, Crestor and Pravachol, lowers blood cholesterol by inhibiting a cholesterol-producing enzyme and may even lower the risks of heart attack and further cardiovascular disease in a narrow category of patients. A new study forthcoming in the American Journal of Cardiology examined the effect of statins on creatine kinase (CK), an enzyme linked to muscle damage. Elevated levels of CK in the blood and muscle after exercise correlates with muscle damage. The study, conducted by Dr Beth Parker of the Henry Low Heart Centre at Connecticut's Hartford Hospital, is the first to measure CK levels in athletes taking statins after physical activity in a real-life environment rather than in a university laboratory.


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